Find Cheap Flights from Santo Domingo (SDQ) to Panama City (PTY) from €476

Many airlines offer flexible change policies

Earn BONUS+ rewards on top of your airline points

Enjoy exclusive promotions on the ebookers app!

Selected flight deals from Santo Domingo to Panama City

The lowest prices found within the past 7 days from Santo Domingo to Panama City were €220 for one-way flights and €476 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 9 May - Sun, 11 May
SDQ
Las Americas Intl.
PTY
Tocumen Intl.
€476 Return, found 6 days ago
€476
Return
found 6 days ago
Select avianca flight, departing Fri, 9 May from Las Americas Intl. to Tocumen Intl., returning Sun, 11 May, priced at €476 found 6 days ago
Fri, 9 May - Sun, 11 May
SDQ
Las Americas Intl.
PTY
Tocumen Intl.
€479 Return, found 6 days ago
€479
Return
found 6 days ago
Select American Airlines flight, departing Fri, 9 May from Las Americas Intl. to Tocumen Intl., returning Sun, 11 May, priced at €479 found 6 days ago
Fri, 9 May - Sun, 11 May
SDQ
Las Americas Intl.
PTY
Tocumen Intl.
€484 Return, found 6 days ago
€484
Return
found 6 days ago
Select avianca flight, departing Fri, 9 May from Las Americas Intl. to Tocumen Intl., returning Sun, 11 May, priced at €484 found 6 days ago
Fri, 9 May - Sun, 11 May
SDQ
Las Americas Intl.
PTY
Tocumen Intl.
€547 Return, found 6 days ago
€547
Return
found 6 days ago
Select American Airlines flight, departing Fri, 9 May from Las Americas Intl. to Tocumen Intl., returning Sun, 11 May, priced at €547 found 6 days ago
Fri, 9 May - Sun, 11 May
SDQ
Las Americas Intl.
PTY
Tocumen Intl.
€584 Return, found 6 days ago
€584
Return
found 6 days ago
Select avianca flight, departing Fri, 9 May from Las Americas Intl. to Tocumen Intl., returning Sun, 11 May, priced at €584 found 6 days ago
Cheap Flights from Santo Domingo to Panama City & Flight Information
Origin airport IATA code
SDQ
Destination airport IATA code
PTY
Return price
€475

Best Day to Book Flight from Santo Domingo to Panama City

Panama City Flight Information

Traveling From
Santo Domingo
Origin Airport IATA Code
SDQ
Traveling To
Panama City
Destination Airport IATA Code
PTY
Number of Airlines Serving
Available Airlines
avianca, American Airlines
Distance
Direct Flight Time
Flight Price
€476

Need a car after flight from Santo Domingo to Panama City

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Santo Domingo to Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Yövy tässä 5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 3 ravintolasta. Asiakkaamme kehuvat ...
9/10 Wonderful! (3,882 reviews)
"Staff are very kind and have all information needed"

Reviewed on 6 May 2025

Hotel Riu Plaza Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Yövy tässä 5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, 4 ulkouima-altaasta ja 3 ravintolasta. Asiakkaamme kehuvat majoituspaikan ...
8.8/10 Excellent! (1,000 reviews)
"Its location and the amenities associated with the hotel. Staff is always friendly and helpful"

Reviewed on 6 May 2025

JW Marriott Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Yövy tässä 3,5 tähden liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...
9.2/10 Wonderful! (2,030 reviews)
"Clean and nice view"

Reviewed on 5 May 2025

Plaza Paitilla Inn Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Riande Urban Hotel

Riande Urban Hotel

3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
Yövy tässä 3,5 tähden liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 2 ravintolasta. ...
8.6/10 Excellent! (1,011 reviews)
"Very comfortable hotel with great amenities. I would stay here again and again. Restaurant, pool, bar, lounging areas and the nicest people working here."

Reviewed on 4 May 2025

Riande Urban Hotel
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Yövy tässä 4 tähden liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, 2 ravintolasta ja 2 baarista/loungesta. Asiakkaamme ...
9/10 Wonderful! (1,002 reviews)
"If you are going to shop at albrook mall then this is the place to stay"

Reviewed on 30 Apr 2025

Marriott Panama Hotel
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
Yövy tässä 4 tähden perheille sopivassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). ...
9/10 Wonderful! (1,015 reviews)
"Great stay in a good safe location in Panama. The staff are very friendly and welcoming."

Reviewed on 2 May 2025

Novotel Panama City
Don't see what you're looking for?
See all available properties in Panama City
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama City Airports

Other Flights to Panama City

Flights from Other Cities

Top Trending

Terms & Conditions

Flight prices above are per person all prepaid taxes and online service fees included and subject to availability