Cheap flights from De Soto

Many airlines offer flexible change policies

Earn BONUS+ rewards on top of your airline points

Enjoy exclusive promotions on the ebookers app!

De Soto Flight Information
Origin airport IATA code
STL

Your cheap flight from De Soto is available right now.

Visit us now at Ebookers to choose from lots of cheap flights leaving De Soto or our last minute air tickets from De Soto at unbeatable prices, specially chosen for those who want the best deal possible. Ebookers continuously compares and updates the choice of air tickets available from De Soto, offered by more than 400 airlines worldwide. Ebookers works 24/7 to find the best deals so that our clients don’t have to waste their valuable time. Wherever you are going, you will find your perfect combination for a fantastic holiday at a budget price right here with our extensive flights database and helpful information; star ratings, reviews, maps and more… Many discount flights with a departure from De Soto and last minute flights from De Soto are available at Ebookers to help you organise your flights the way you want them at a price you can afford. Come and prepare your perfect holiday now at Ebookers.

Fancy a break from De Soto? Book your flight in advance from De Soto!

Thinking about getting away for a while and leaving from De Soto? Visit Ebookers and discover our selection of inexpensive De Soto flights and air tickets from De Soto at unbelievable prices with a great choice of airlines - over 400 in fact. We give excellent service at an affordable price. For a great weekend away from De Soto, visit to Ebookers where we have many available flights departing De Soto on special offer. Check out our deals and find a flight leaving De Soto at a price you never imagined. These special Ebookers offers aren’t just about cheap flights. We have over 95,000 hotels worldwide in our database, so why not stay in a De Soto hotel and start or end your break in style? Combine your choice of flight, hotel and car rental from our vast, reliable database to create your perfect holiday or dream weekend at a discounted price with Ebookers. Don’t wait or you may be too late!

Featured Hotels near De Soto

Secluded cabin on private property

Secluded cabin on private property

De Soto, MO
During your stay at this cabin, you're just a quick walk from Big River. The cabin offers free WiFi and a kitchen.
10/10 Exceptional! (45 reviews)
Private Ridge Top
"Great house, beautiful property, small trails around property for your dogs. Nice retreat."

Reviewed on 22 Mar 2025

Secluded cabin on private property
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto, MO
The price is €260 per night from 5 Apr to 6 Apr
€260
per night
5 Apr - 6 Apr
During your stay at this cabin, you'll be close to Eastside Community Park. The cabin includes amenities such as a kitchen and a patio.
10/10 Exceptional! (34 reviews)
Mar. 8 for DeSoto High School Musical
"We had a great time staying at Teresia's AirBnb! Convenient location for our needs. She stayed in contact with us regularly and was so helpful. I can't say enough good things about her and about the log cabin. It is decorated so cute, if I could give 100 stars for cleanliness and her hospitality ..."

Reviewed on 10 Mar 2025

82 Acre Hobby Farm with Lincoln Log Cabin
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
The price is €166 per night from 6 Apr to 7 Apr
€166
per night
6 Apr - 7 Apr
Our customers tell us that they enjoy the overall property condition at Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG. During your stay, you'll be close to Valle Lake Beach. Enjoy features like free self-parking, plus a gym and a snack bar/deli. Built in 1998, this comfortable aparthotel has 72 apartments over 3 floors. A furnished balcony/patio and a flat-screen TV are available in each apartment.
9.2/10 Wonderful! (139 reviews)
"Many things to do if you don't want to go anywhere. Close to shopping, restaurant."

Reviewed on 30 Dec 2024

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Save an average of 15% on thousands of hotels when you're signed in
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln, Arnold, MO
The price is €94 per night from 9 Apr to 10 Apr
€94
per night
9 Apr - 10 Apr
Our customers tell us that they enjoy the free breakfast at Pear Tree Inn St. Louis Arnold. During your stay, you'll be within walking distance of Arnold Historical Society & Museum. Features include free WiFi in public areas, free self-parking and a free manager's reception.
9.2/10 Wonderful! (1,000 reviews)
"Staff was helpful."

Reviewed on 30 Mar 2025

Pear Tree Inn St. Louis Arnold
Lakeside Private Villa | 5-Hole Golf On-Site

Lakeside Private Villa | 5-Hole Golf On-Site

4800 US Highway 67, Desoto, MO
During your stay at this villa, you'll be close to Valle Lake Beach. Enjoy features like an arcade/games room. Free WiFi and a kitchen are available in the villa.
8.8/10 Excellent! (12 reviews)
Convenient to DeSoto
"The place was clean and we loved the two bedrooms with full bath. The bed is fantastic which was really the purpose Of staying there. I do feel the description is a bit misleading in that the advertisement made it sound like the lake was in view and that it was a stand alone house, not a condo. I ..."

Reviewed on 28 Mar 2023

Lakeside Private Villa | 5-Hole Golf On-Site
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
The price is €55 per night from 27 Apr to 28 Apr
€55
per night
27 Apr - 28 Apr
Our customers tell us that they enjoy the free breakfast at Baymont Inn and Suites by Wyndham Farmington, MO. During your stay, you'll be within walking distance of Parkland Health Center. Free WiFi in public areas, free self-parking and a 24-hour gym are available.
8/10 Very Good! (901 reviews)
"Great stay."

Reviewed on 1 Apr 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Don't see what you're looking for?
See all available properties in De Soto
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.