Find 3,621 hotels in San Diego Santa Fe Depot

The Dana on Mission Bay's great beach location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. You'll find features such as free WiFi in public areas, plus 2 outdoor pools and 2 poolside bars. This property offers pet-friendly amenities, such as food and water bowls.

The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from USS Midway Museum. Enjoy features like a free round-trip airport shuttle, plus 2 restaurants and an outdoor pool.

Our customers tell us they can't get enough of Omni San Diego Hotel's great location. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus an outdoor pool and a 24-hour gym.

Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.

Hyatt Regency Mission Bay Spa and Marina's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 2 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us that they can't get enough of the free breakfast at Comfort Inn Sea World Area. During your stay, you're just a quick walk from Pechanga Arena. You'll find features such as free WiFi in public areas and free self-parking, plus a gym.

The shopping around Sheraton Mission Valley San Diego Hotel gets high marks from our customers. During your stay, you'll be within walking distance of Mission Valley Mall. Free WiFi in public areas, an outdoor pool and a restaurant are available. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us they can't get enough of Handlery Hotel's great location. During your stay, you'll be within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus 2 restaurants and 2 bars.

Humphreys Half Moon Inn's great location gets high marks from our customers. During your stay, you're just a quick walk from San Diego Bay. Enjoy features like an outdoor pool, a restaurant and a marina.

Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from San Diego Bay. You'll find features such as a free round-trip airport shuttle, plus 3 outdoor pools and 5 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.

Our customers tell us they can't get enough of Kings Inn San Diego's great location. During your stay, you'll be within walking distance of Riverwalk Golf Club. Features include free WiFi in public areas, plus 2 restaurants and an outdoor pool.

Our customers tell us that they can't get enough of the helpful staff at The Sofia Hotel. During your stay, you're just a quick walk from San Diego Civic Theatre. Free WiFi in public areas, a full-service spa and a restaurant are available. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us that they can't get enough of the comfortable beds at The Horton Grand, Downtown/Gaslamp Quarter. During your stay, you're just a quick walk from Petco Park. Enjoy features like a restaurant, a gym and a bar.

Our customers tell us they can't get enough of Bay Club Hotel & Marina's great location. During your stay, you're just a quick walk from San Diego Bay. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant.